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Intracellular pH is a key parameter related to various biological and pathological processes.In this study,a ratiometric......
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Design and Synthesis of Isopropanol-bridged Sulfonyl Carbazoles as Novel Potential Antimicrobial Age
Natural and synthetic congeners of carbazole comprise a large group of therapeutically useful agents in medicinal chemis......
A Unique C-N Breakage of Sulfonylated Cyclic Amines by Azole Ring to Access Novel Antimicrobial Sulf
Sulfonamides are extensively employed as artificial antifolic agents for the prevention and cure of bacterial infections......
Synthesis and biological evaluation of novel indole derivatives containing sulfonamide scaffold as p
Microtubule-targeted drugs play a critical role in various types of cancer therapy worldwide.In our study,a series o......
In view of quantum pharmacology, the structure-activity relationships of different kinds of fused heterocydic sulfonamid......
A novel series of diaryl urea derivatives bearing sulfonamide moiety have been designed and synthesized.Their in vitro a......
建立了一种同时分离测定血浆中12种磺胺类药物的高效合相色谱(Ultra Performance Convergence Chromatography,UPC2)方法.血浆样品......
4-((4-Chlorophenylsulfonamido)methyl)cyclohexanecarboxylic Acid: Synthesis, Crystal Structure and Bi
In this study, a novel 4-((4-chlorophenylsulfonamido)methyl)cyclohexanecarboxylic acid(C_(14)H_(18)ClNO_4S) was synthesi......
,A novel sulfonamide agent, MPSP-001, exhibits potent activity against human cancer cells in vitro t
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,Design, molecular docking, synthesis, characterization, biological activity evaluation (against MES
BACKGROUND:Among the reported potential agents to treat the epilepsy,sulphonamides are important and their significance ......
Synthesis, Crystal Structure and Antibacterial Activity of New N-(1H-benzo [d]imidazol-2-yl)benzenes
The title compounds (7a～7g) were synthesized from dehydroabietic acid and characterized by spectroscopic methods includin......
OH addition reactions of cationic,neutral and anionic forms of three sulfonamides (sulfamethoxazole,sulfadiazine and sul......
本文通过对荣华二采区10...
Design,Synthesis and Biological Activities of Novel Amides (Sulfonamides) Containing N-Pyridylpyrazo
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
Synthesis and Antimicrobial Activity of Quinazolin-4(3H)-ones Incorporating Sulfonamido-4-thiazolidi
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
In Situ Generation of Oxazole Ylide and Interception with Sulfonamide: Construction of Amidines Usin
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
目的建立土壤中11种磺胺类兽用抗生素的超高效液相色谱-串联质谱测定法。方法样品用0.1 mol/LEDTA提取液(乙腈∶柠檬酸=1∶1)提取,......
Two new chiral Ru(II)-sulfonamide complex have been used to catalyze the enantioselective transfer hydrogenation of proc......
目的:获取15种磺胺类药物(SAs)的ESI正离子模式下高分辨质谱碎片信息,并研究其裂解规律,探讨高能诱导裂解(HCD)技术的应用价值.方......
对125个磺胺类碳酸酐酶Ⅱ抑制剂的生物活性进行了预测研究.利用ADRIANA.Code软件计算得到了化合物的一系列2D和3D结构描述符,从中......
The crystal structure of 2-nitrophenyl N,N-bis(2-chloroethyl)-N'-(4-methylben-zene-sulfonamino)ethyl-phosphorodiamidate ......
Sulfonamide residue in honey existed in a form bonded to sugar via the N-glycosidic bond.It would result in the possible......
以3-（4-氯磺酰苯基）-2，3-二溴丙酸（1mmol）和氨水（2．2mmol）为原料，以DMF为溶剂，经微波辐射25s，磺酰胺化和脱溴脱羧反应可同步进行，立体选择性合......
建立了化妆品中12种磺胺类药物的高效液相色谱-串联四极杆质谱联用测定方法。该方法经乙腈提取样品,以资生堂MGⅢ-C18柱（2.1 mm......
磺酰脲类除草剂以其超高效、低毒和高选择性而著称,它通过抑制植物体内ALS酶的活性来破坏支链氨基酸的生物合成从而使杂草死亡. Le......
报道了KF作用下离子液体介质中N-单取代磺酰胺和卤代烃的N-烷基化反应,考察了4种不同结构的离子液体[Bmim]BF4、[Bpy]BF4和[Bpy]PF......
建立了一种液相色谱-电喷雾串联质谱同时测定中华绒螯蟹中21种磺胺类药物残留的方法。均质样品先后用乙腈、二氯甲烷提取,合并提取......
以4,6-二异戊氧基-1,3-二磺酰氯和N,N-二甲基羟基胺为原料,三乙胺作催化剂,二氯甲烷作溶剂,采取一锅煮反应的方法合成了1种N,N-二......
采用紫外光谱法测定Cu^2＋和Bi^3＋的浓度,选择在最大吸收波长280和320nm处,分析Cu^2＋和Bi^3＋的浓度与紫外光谱的吸光度数值之间的相关性......
食品中抗生素的残留威胁着消费者的健康。目前用于食品中抗生素残留的检测方法通常经过复杂的预处理、耗时繁琐，而荧光检测具有快速......
模拟磺胺母核结构合成了3种人工免疫原，免疫新西兰白兔，用间接竞争ELISA方法监测免疫效果。选择抑制效果较好的2组多抗血清建立磺胺......
通过溶荆提取分离、液相色谱-电喷雾质谱联用技术定量测定肉制品中常见的9类磺胺类药物（磺胺嘧啶、磺胺吡啶、磺胺甲嘧啶、磺胺二甲......
为了解犊牛磺胺中毒的病理形态学变化特点,对2头因磺胺中毒而死亡的犊牛进行了详细的病理学研究。结果表明,犊牛磺胺中毒的病理性......
研究了广州市典型有机蔬菜基地土壤中8种磺胺类抗生素（SAs）的污染特征和风险水平.结果表明,8种SAs在土壤中普遍检出（检出率≥94%）,总含......
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本文以重氮偶合比色法(以下称B-M比色法)或高效液相色谱(以下简称HPLC)法,对磺胺药和三甲氧苄胺嘧啶(TMP)在马体内代谢动力学特征......
综述了动物源性食品中磺胺类药物多残留检测的酶联免疫测定方法研究进展。分别对磺胺药物特异性抗体制备的基本原理，载体与半抗原的......
建立了蜂蜜中11种磺胺类药物残留的高效液相色谱-串联四极杆质谱联用测定方法。该方法经乙腈提取样品,以ZORBAXAq-C18柱（2.1×1......
以4，6-二异戊氧基-1，3-苯二磺酰氯为原料，三乙胺作缚酸剂，二氯甲烷或丙酮作溶剂，合成了4，6-二异戊氧基-1，3-二苯磺酸喹啉-8-酯（2）、4，6-二异......
磺胺类抗生素(SAs)在医药和养殖领域广泛使用,使自然水体中SAs残留量不断增加。SAs对水生态系统的危害方面已多有报道,然而,关于其......
提出了应用超高效液相色谱-串联质谱法测定动物组织中13种磺胺和6种喹诺酮类兽药残留量的方法。采用乙腈萃取动物组织中兽药成分,......
本文以磺胺以及衍生物分子的印迹聚合物体系为研究对象，借助计算机模拟，利用分子动力学研究功能单体与模板分子之间的相互作用力情况......
根据高效毛细管电泳的原理,用毛细管电泳分析法对两种拮抗药物一对氨基苯甲酸和磺胺进行了分离测定该法分离效果好,分析速度快,测......
为了揭示海陆衔接区环境中抗生素与抗性细菌分布特征及其内在相关性，以莱州湾及其主要人海河流为研究区域．利用HPLC-MS／MS分析样品中1......
应用4株磺胺二甲基嘧啶（SMZ）多克隆抗体和5种不同结构的荧光标记物（Tracer）建立了荧光偏振免疫分析（FPIA）检测SMZ的方法.讨论了4株多抗对......
